HAVCR2 and neoplasm: Recently, a report was published describing an association between myasthenia gravis-associated thymoma and T cell immunoglobulin and mucin domain-3 (Tim-3), which is a subtype of the Tim protein family.10 Plasma exchange generally performed to remove pathogenic autoantibodies, immune complexes, cryoglobulins, and toxins that have accumulated in the plasma,11 which may eliminate the components stimulating tumor grow and show antitumor efficacy.