As MAPT is 1 of the most important susceptibility genes for PD, we further performed a sensitivity analysis for the 13 SNPs identified in Model 2 by removing potential PD cases based on self-reported physician diagnosis or use of PD medications (90 in ARIC, 14 in Health ABC, and 12 in ROS/MAP) and obtained similar results (Table S7, http://links.lww.com/MD/A526). This evidence concerns the gene MAPT and Parkinson disease.