EZR and cancer: Numerous epidemiological studies have also assessed the correlation of high Ezrin expression and poor outcome in cancer patients so far, such as digestive system cancer16, 17, 18, 19, 20, 21, 22, 23, 24, 25, osteosarcoma26, 27, 28, 29, 30, 31, 79, 80, HNSCC32, 33, 34, 35, 36, gynecologic cancer37, 38, 39, hepatobiliary cancer43 and so on.