In addition, because tumor cells are reported to use immunomodulatory soluble factors such as IL-6, IL-8, IL-10 and PGE2 for immune evasion27, 28, 29, 30, 31, we next detected the concentration of these soluble factors secreted by MCF-7 cells after STB-HO treatment. The gene discussed is CXCL8; the disease is neoplasm.