The current version of OMIM shows an association between Leukemia and the gene PDGFRB, which interacts with PDGFB a gene associated to Dermatofibrosarcoma; the “old” score between Right Atrial Isomerism and Tetralogy of Fallot (MIM: 187500) is in the 100th percentile and now it has been shown that they share a disease gene (GDF1). The gene discussed is PDGFB; the disease is Tetralogy of Fallot.