Of note, the TRP2-specific CD8+ T cells induced by vaccination with Dexo(B16 + pIC) also showed increased expression of the effector memory phenotype markers CD62L-CD44+, with 22.28%, 0.94% and 88.1% of CD62L-CD44+TRP2-specific CD8+ T lymphocytes detected in the tdLNs, spleens and tumor masses, respectively (Fig. 5d). This evidence concerns the gene CD44 and neoplasm.