BRCA1 and neoplasm: However, as mentioned previously, BRCA1 rs8176318 was associated with the G allele specific (C in our tables) miRNA hsa-miR-525-5p and we did see a reduction in expression of hsa-miR-525-5p in non-tumor tissues with the variant allele as well as a lowered level of mean miRNA expression in tumor tissue as compared to non-tumor tissue.