CRH and Anxiety: Moreover, CRF and its related peptides also exert central functions and influence a variety of non-social and social behaviors, e.g., increased anxiety-related behavior (Britton et al., 1986, Klampfl et al., 2014, Klampfl et al., 2013, Sahuque et al., 2006) and reduced maternal behavior (Gammie et al., 2004, Klampfl et al., 2014, Klampfl et al., 2013, Pedersen et al., 1991), even leading to pup killing in virgin rats (Pedersen et al., 1991).