Comparison of demographic data and clinical characteristics between patients from the two center reveal significant differences in age, gender (47.44% men VS 58.62%), the proportion of diabetes (33.48% VS 1.72%) and cardiovascular disease (28.37% VS 13.79%), hemoglobin ((114.04 VS 90.47)g/L), serum albumin ((39.02 VS 29.27) g/L),Triglycerides ((2.22 VS 1.34)mmol/L), corrected calcium ((2.39 VS 2.28)mmol/L) and intact parathyroid hormone (165.60 VS 272.00)pg/ml). The gene discussed is ALB; the disease is diabetes mellitus.