Ongoing work is aimed at characterizing the expression of other regulatory T cell markers such as FoxP3 and/or CD62L in this putative Treg population and determining if adoptive transfer of a CD4+ T cell pool from hESC-MSC-treated animals may protect or alter the time course for disease progression in naïve lupus-prone mice. The gene discussed is CD4; the disease is systemic lupus erythematosus.