MBP and multiple system atrophy: The development of a transgenic mouse model which reproduces GCI-like aggregations by overexpression of α-syn under control of the proteolipid-protein promoter (PLP) [13] or the myelin basic protein (MBP) [14] in oligodendroglial cells has been instrumental to address mechanisms of MSA-like neurodegeneration [12, 15–19].