INS and metabolic syndrome: In our long-term (18 wk) feeding study, saury oil enriched in n-3 PUFA and LCMUFA significantly improved risk factors for metabolic syndrome in diet-induced obese mice, by possible combined effects of EPA and LCMUFA on altering plasma lipid levels, as well as by other mechanisms, such as favourable changes on hepatic lipid deposition, plasma insulin levels, and the fatty acid desaturation index in adipose tissue.