IL-1Ra, IL-8 and IL-17a were for TLE (P = 0.020, 0.012 and 0.021, respectively), IL-17a and all IFNλs were for XLE (P = 0.049, 0.025, 0.049, <0.001 and 0.006), and IL-1Ra, IL-8, IFNλ1, and IFNλ4 were for IGE (P = 0.009, 0.005, 0.011 and 0.043 respectively). This evidence concerns the gene IFNL4 and idiopathic generalized epilepsy.