After 72 h co-culture, the number of B16 melanoma cells that were co-cultured with 9-HODE pre-treated lal−/− Ly6G+ cells was significantly less (Figure 2C), suggesting the ability of lal−/− Ly6G+ cells to promote melanoma cell proliferation was impaired by PPARγ ligand treatment. The gene discussed is PPARG; the disease is melanoma.