Under the addition of DMSO, T24 Mut shETS1 and T24 Mut Double sh displayed a remarkable decrease in tumor volume, which suggested that the depletion of ETS1 (31.85%, P < 0.05) and both of GATA4 and ETS1 (41.16%, P < 0.05) inhibited the growth of T24 Mut cells (Figure 5C). This evidence concerns the gene ETS1 and neoplasm.