In addition to MMD and ITPR3, 5 other genes have not been previously documented as related to thyroid cancer or BRAFV600E: AACS, PVRL3, RASA1, ALDH3B1, and LAD1. The knowledge about the potential role in tumorigenesis of these genes is poor, and further studies are essential. The gene discussed is ITPR3; the disease is thyroid cancer.