Interestingly, we observed that in K-562 and HL-60 leukemia cells, while 24 h Gln withdrawal led to an inhibition of the mTOR pathway (as probed by the downstream inhibition of the phosphorylation of S6RP), a compensatory mechanism restored (in the next 24 hours) the phospho-S6RP signal despite the maintained Gln withdrawal (Figure 2C). Here, MTOR is linked to leukemia.