No significant difference was observed between the 6 patients (40.0%) receiving once daily insulin (in the evening or before bedtime) and the 17 patients (34.7%) receiving twice daily insulin (once in the morning and once in the evening or before bed) with regard to the frequency of nocturnal asymptomatic hypoglycemia experienced due to the difference in the timing of basal insulin between the two groups (P = 0.71; χ2 test). Here, INS is linked to Hypoglycemia.