Further analysis found that co-expression of TPX2 and PD-L1 was significantly higher in CIN persistence/recurrence group than in no persistence/recurrence group (p = 0.013) and there was also significant difference in co-expression of TPX2 and PD-L1 between CIN1/Normal group and CIN2-3 group (p = 0.014, see Table 5). This evidence concerns the gene CD274 and cervical squamous intraepithelial neoplasia.