At the AP3S2 locus, the T2D GWAS signal[3] coincided with an islet eQTL for AP3S2, encoding adaptor-related protein complex 3, sigma 2 subunit (exon permuted p = 1.0x10-4, q = 0.006, ß = -0.55). Here, AP2S1 is linked to type 2 diabetes mellitus.