MT2A and posterior cortical atrophy: Subsequent multivariate Cox analysis revealed that MT-2A [hazard ratio (HR)=2.01; 95% confidence interval (CI)=1.08–3.15; P=0.005], E-cadherin (HR=1.79; 95% CI=1.08–2.21; P=0.042) and cyclin E (HR=1.92; 95% CI=1.22–2.45; P=0.020) were independent predictors of the biochemical recurrence of PCa.