Furthermore, the risk classification and pathological T (pT) stage of PCa were found to be positively associated with MT-2A (P=0.042 and 0.015), IL-6 (P=0.031 and 0.019) and cyclin-E expression (P=0.039 and 0.043), but inversely correlated with E-cadherin expression (P=0.032 and 0.012) (Table I). This evidence concerns the gene CDH1 and posterior cortical atrophy.