A more recent study by Oliviera et al defined high cellularity, large tumor size, presence of anaplasia or rhabdoid features, high mitotic activity (>2 per 10 high-power fields) and proliferative activity (Ki-67, ≥10%; Ki-67 ‘hot spot’, ≥25%) as adverse prognostic factors (37). Here, MKI67 is linked to neoplasm.