DAB2IP and posterior cortical atrophy: DAB2IP is a unique scaffold protein that modulates a variety of biological activities, including cell growth, apoptosis and survival via the phosphoinositide 3-kinase-Akt, Wnt-epithelial-mesenchymal transition, ASK-JNK, Ras-mitogen-activated protein kinase, and nuclear factor-κB pathways in PCa (4,7–9).