BRD2 and ovarian hyperstimulation syndrome: Due to the high sensitivity of the ovaries to gonadotropin stimulation, treatment with human menopausal gonadotropin or pure follicle-stimulating hormone (FSH) is challenging to control and is individually administered to induce several ovulatory follicles, which incurs a substantial increased risk of multiple pregnancies and ovarian hyperstimulation syndrome (OHSS) (6).