IBC-NED with low DCLK1 expression showed the lowest DFS rate, when compared to non-NED luminal cancers regardless of the neuroendocrine expression pattern (DCLK1 low/ neuroendocrine focal: log-rank=8.861, p = 0.003; DCLK1 low/ neuroendocrine diffuse: log-rank=7.211, p = 0.007) (Figure 3). The gene discussed is DCLK1; the disease is cancer.