PROCR and anemia (phenotype): The mechanisms resulting in the development of severe malaria have not yet been fully understood, however; recently, the endothelial protein C receptor (EPCR) has been identified as a specific receptor for the P. falciparum erythrocyte membrane protein 1 (PfEMP1) variants mediating sequestration of infected erythrocytes in the most severe forms of malaria, including severe anaemia and cerebral malaria [3, 4].