CRP had 100 % sensitivity and only 46 % specificity when distinguishing TB from malignant effusions [35], while in another study its sensitivity was 74 % and its specificity 77 %, respectively [36], findings that were verified by a third study, in which CRP performed poorly (AUC = 0.57 vs. 0.86 for YKL-40 in ours) and only ADA performed extremely well (AUC = 0.94) [37]. This evidence concerns the gene CHI3L1 and tuberculosis.