1996; Braziel et al. 2002; O’Brien et al. 2003). Recently, imatinib has been shown to attenuate pulmonary vascular injury and prevent pulmonary edema in a number of injury models, including thrombin, histamine, vascular endothelial growth factor, oxidant injury, cecal ligation and puncture, and intratracheal LPS (Aman et al. 2012; Kim et al. 2013b; Stephens et al. 2014; Letsiou et al. 2015). This evidence concerns the gene VEGFA and pulmonary edema.