Other differential diagnoses for bilateral adrenal masses/abnormalities in the setting of suppressed ACTH are AIMAH (usually associated with a macronodular appearance), bilateral cortisol-secreting adenomas/adenolipomas [10], or a unilateral adrenal adenoma with contralateral nonfunctioning incidentaloma. The gene discussed is POMC; the disease is Cushing syndrome due to macronodular adrenal hyperplasia.