In PtA (circle III in Figure 4a), all tumor regions shared four common actionable mutated genes (MTFHR, MYH11, ABCC4 and GPRC6A); in PtB (circle III in Figure 4b), all tumor regions, including the metastasis, shared five druggable mutated genes (TP53, GPR37, HGF, CENPE and HTR3D). This evidence concerns the gene MYH11 and neoplasm.