IFNAR1 and viral infectious disease: Before virus infection, the frequency and number of CD3−NK1.1+DX5+ NK cells were comparable in vaginal tract and iliac LN of both BL/6 and IFNAR KO mice, except liver tissue (S3 Fig), which indicates that IFN-I signaling may not contribute to basal recruitment of NK cells in primary target tissues of HSV-1 mucosal infection.