IFNG and tuberculosis: In mice, allelic variations within the H2 complex were shown to affect survival time following challenge, the level of T-lymphocyte-mediated delayed type hypersensitivity (DTH) response, T-cell proliferation after stimulation with mycobacterial antigens and the efficacy of BCG vaccination against tuberculosis, production of IFN-γ by mycobacteria-specific T-cells, and production of mycobacteria-specific antibodies [31, 36–39].