A recent analysis encompassing 6934 subjects indicated that the GSTM1-null genotype was significantly associated with idiopathic oligozoospermia, while the null genotype of GSTT1 was significantly associated with normozoospermia and azoospermia, and the association between GSTM1 polymorphism and male infertility was observed in cohorts of both Asian and Caucasian groups [84]. This evidence concerns the gene GSTM1 and male infertility.