It is not known what effect loss of ABCA1 or SR-B1 protein expression either globally or myeloid-specifically has on tumorigenesis but by extrapolation from tumor studies in mice with ABCG1 loss, one might predict a protective effect due to the heightened pro-inflammatory phenotype these transporter-/receptor-deleted macrophages are known to exhibit. This evidence concerns the gene ABCG1 and neoplasm.