It has been shown that ALK inhibitor-resistant non-small-cell lung cancer cell lines are susceptible to heat-shock protein 90 (HSP90) inhibitors.27 Moreover, AXL is an acknowledged substrate of HSP90,28 prompting us to investigate the consequences of HSP90 inhibition in the context of NB cell resistance to TAE684. Here, ALK is linked to non-small cell lung carcinoma.