Although their lifespans are not reduced compared to normal control mice, Immp2l−/− mice show erectile dysfunction, defective oogenesis (Lu et al., 2008), reduced food intake (Han et al., 2013), bladder dysfunction (Soler et al., 2010), early onset of ataxia and kyphosis (George et al., 2011), and age‐dependent spermatogenic damage (Lu et al., 2008; George et al., 2012). The gene discussed is IMMP2L; the disease is cerebellar ataxia.