MUC2 and colorectal cancer: In this study, we investigated the anti-inflammatory activity of MBF extracts in lipopolysaccharide (LPS) stimulated RAW264.7 macrophage cells, and the therapeutic efficacy of MBF diet in dextran sulfate sodium (DSS) exposed mice and MUC2−/− mice, which represent the acute colitis (AC) and colorectal cancer (CRC) models, respectively.