MUC2 and colorectal carcinoma: Our results demonstrated that MBF extracts inhibited the expression of proinflammatory mediators by blocking both the NFκB/p65 and pERK/MAPK signals in LPS-induced macrophage cells, and the MBF diet showed significant inhibitory effects on the development of DSS-induced AC and the progress of CRC in MUC2−/− mice.