In this cohort, we demonstrated the upregulated expression of CEP55 in EOC cells and surgical specimens and reported, for the first time, the correlation of CEP55 protein expression with clinical stage, lymph node metastasis, intraperitoneal metastasis, tumor recurrence, differentiation grade, residual tumor size, ascites see tumor cells, serum CA153 level, as well as prognosis in patients with EOC. The gene discussed is CEP55; the disease is neoplasm.