CRP and rheumatoid arthritis: In this article, we investigate the efficacy of CZP in patients with RA with regard to PROs of physical function, pain, fatigue, sleep, and PtGA in the REALISTIC study and examine the correlations between PROs and clinical indices of RA signs and symptoms, including the Disease Activity Score in 28 joints using C-reactive protein (DAS28[CRP]) and formal joint counts.