FCGR3A and infection: Furthermore, in a logistic regression controlling for factors associated with maternal transmission (plasma viral load, breastfeeding, and infant prematurity), the heterozygote genotype (V/F) was significantly associated with increased odds of infant infection compared with FCGR3A low-affinity homozygotes (F/F) (OR = 2.17; 95% CI, 1.11–4.24; P = .02).