As Hes1, a canonical Notch1 target, is able to induce NF‐κB activation in human T‐cell leukaemia and animal models of the disease 24, we speculate that Notch1 might down‐regulate miR‐124 through activation of the NF‐κB pathway in GC cells, but this hypothesis needs further study. This evidence concerns the gene NOTCH1 and gastric cancer.