WNK2 and hepatocellular carcinoma: Additionally, it was also found high expression of LncRNA URHC (upregulated in hepatocellular carcinoma) can inhibit apoptosis through repressing expression of ZAK (sterile alpha motif and leucine zipper containing kinase AZK), a regulator of the ERK (extracellular regulated protein kinases)/MAPK (mitogen-activated protein kinase) pathway, in hepatocellular carcinoma [23].