We suggest the following diagnostic approach for patients with retinitis with a history of recent fever in Indian scenario: After ruling out hypertensive and diabetic retinopathy, a baseline blood investigations including total and differential counts, erythrocyte sedimentation rate (ESR), TPHA or rapid plasma reagin (RPR), HIV, anti-nuclear antibody (ANA), and toxoplasma serology should be done. The gene discussed is BTG3; the disease is retinitis.