In the present investigation, these characteristics were exploited to meet the clinical need for a corresponding gamma-emitting probe, which on the one hand allows for the intraoperative detection and identification of PSMA-positive tissues during surgery in patients with early recurrent or primary advanced PCa and on the other hand may additionally be employed for (preoperative) SPECT imaging (Fig. 1). The gene discussed is FOLH1; the disease is posterior cortical atrophy.