Besides cell invasion, we found that TSG101 depletion did not affect cell growth or cell migration of HT1080 or HeLaS3 cells, although it was reported that TSG101 depletion inhibits cell growth and cell migration of prostate cancer PC3, breast cancer MDA-MB-231, and breast cancer MCF-7 cells [19, 20]. Here, TSG101 is linked to Familial prostate cancer.