The secretion of other angiogenic and growth factors like Growth related oncogene (GRO), Growth related oncogene-alpha (GROα), urokinase plaminogen activator receptor (uPAR), Oncostatin M (OSM), soluble tumor necrosis factor-alpha receptor 1 (sTNFRI), Intercellular adhesion molecule 1 (ICAM-1) was increased in the conditioned media of breast cancer cells when compared to control HMEC cells conditioned media (Additional file 1: Figure S1). This evidence concerns the gene PLAUR and breast carcinoma.