There was a consistent high expression of OPG in the invasive ductal carcinoma breast tissue samples (Fig. 3c, panels a1, b1, a2, b2, a4, b4, d5 and e5) when compared to the control uninvolved tissue samples (Fig. 3c, panels c2, c4 and f5). The gene discussed is TNFRSF11B; the disease is invasive ductal breast carcinoma.