INS and type 2 diabetes mellitus: Significant associations were found between rs2206447 and T2DM (P = 0.008, FUSION Study), and between rs6080705 and HOMA-beta (P = 0.008588), HOMA-IR (P = 0.02582) and fasting insulin (P = 0.01508) (https://www.gwascentral.org/, searched on 6.10.2014) (Table 5).