Calpain 10 (CAPN10)14, ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1)15, hepatocyte nuclear factor 4α (HNF4A)16, 17, adiponectin (ADIPOQ)18, and transcription factor 7-like 2 (TCF7L2)19 were previously identified in T2DM-linked chromosomal regions. The gene discussed is ENPP1; the disease is type 2 diabetes mellitus.