LRRC24 and Dravet syndrome: Our bis-seq data also validated and extended the BeadChip findings of gains of methylation in a CGI overlapping intron 1 of the CPT1B gene, and showed the presence of DS-DM at multiple CpGs in a regulatory region of the LRRC14/LRRC24 leucine-rich repeat gene pair (Figure S4 in Additional file 1).