TIMP2 and acute kidney injury: As shown in Fig 4, ROC curve analysis for the accuracy of [TIMP-2]•[IGFBP7] in prediction of 30-day mortality revealed an AUC of 0.79 (95% CI: 0.61–0.97) when analyzed for the AKI group and an AUC of 0.84 (95% CI: 0.70–0.98) for all inpatients, i.e. AKI patients and non-AKI PICU/NICU patients (n = 63).