Asphyctic newborns with AKI had 4.3-fold (P = 0.02) higher urinary [TIMP-2]•[IGFBP7] values (0.47, 0.15 to 1.31; n = 9) than newborns of non-AKI group I+II (0.11, 0.06 to 0.27; n = 22). This evidence concerns the gene IGFBP7 and acute kidney injury.