Furthermore, this kinase mediates the full activation of AKT activity, regulates GLUT4 translocation by insulin in skeletal muscle, and may even regulate adipocyte differentiation, which may in part explain the postprandial dysglycaemia evident in people with ataxia telangiectasia 12, 13. The gene discussed is SLC2A4; the disease is Ataxia-telangiectasia.